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Association of Official Racing Chemists guidelines for drug testing in animal hair for doping control
The Association of Official Racing Chemists (AORC) guidelines for drug testing in animal hair provide animal sport doping control laboratories…
The use of sequential window acquisition of all theoretical fragment ion spectra (SWATH), a data‐independent acquisition high‐resolution mass spectrometry approach, in forensic toxicological regimes: A review
A review of 17 publications assessing SWATH in forensic toxicology was conducted, highlighting key parameters such as LC and MS…
Dr David Lloyd Crone, PhD EurChem CChem FRSC FAORC, 1941–2019
Drug Testing and Analysis, Volume 17, Issue 2, Page 299-299, February 2025.
Volumetric dried blood spots for determination of phosphatidylethanol: Validation of a liquid chromatography tandem masspectrometry method and clinical application
Phosphatidylethanol, a specific alcohol biomarker, measured in dried blood spots was the focus of this work. A liquid chromatography tandem…
Individual identification method using samples associated with doping tests: A comparison of mitochondrial and nuclear genetic data
DNA analysis is used to detect attempts at manipulating or substituting samples during doping control. To determine a suitable method,…
Why the racing industry and equestrian disciplines need to implement population pharmacokinetics: To learn, explain, summarize, harmonize, and individualize
Population pharmacokinetics (POP PK) is a pharmacokinetic tool, which measures and explains the variability in drug exposure and drug effect…
Metabolism of highly potent synthetic opioid nitazene analogs: N‐ethyl‐N‐(1‐glucuronyloxyethyl) metabolite formation and degradation to N‐desethyl metabolites during enzymatic hydrolysis
This study revealed that nitazene analogs were mainly metabolized by N-1-hydroxylation followed by glucuronidation, N-deethylation, O-dealkylation followed by glucuronidation, and…
Urinary metabolites indicative of the administration of hypoxen monitored by liquid chromatography–high resolution/accurate mass tandem mass spectrometry
First data on suitable urinary markers indicative of the administration of the poly(dihydroxyphenylene) thiosulfonate-based drug hypoxen were generated, which can…