AUSTRALIAN research has shown support for the efficacy of an oral, plant-based formulation derived from the Khaya senegalensis (KS) tree for treating menstrual pain and premenstrual syndrome (PMS) symptoms, including psychological distress.

KS has been traditionally used in Western herbal medicine to help relieve dysmenorrhoea and mild symptoms associated with PMS, such as mild anxiety.

Eighty-four women experiencing menstrual pain and distress were supplemented 3g daily with the KS preparation or placebo for one menstrual cycle.

Changes in menstrual pain and other symptoms of menstrual distress were examined through daily ratings and validated self-report questionnaires.

Compared to placebo, the KS preparation was associated with greater reductions in the primary outcome measure of daily menstrual pain ratings (46% reduction for KS vs 20% for placebo) and reductions in overall menstrual distress (36% vs 12% respectively).

The KS preparation was well-tolerated and there were no significant safety signals.

“Menstrual health has been under-served for too long,” said lead investigator and MD of Clinical Research Australia, Dr Adrian Lopresti.

“This study highlights the potential of a non-hormonal preparation to offer dual-action benefits – reducing physical discomfort while supporting aspects of psychological wellbeing associated with PMS, such as mood changes and anxiety.”

The study authors noted that more research over a longer duration than one menstrual cycle is needed to determine long-term safety and efficacy.

Read the paper HERE.

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