When Oxybutynin Becomes a Decoy for Oxycodone: A Case Report of Diversion Through Substitution
Drug substitution through visual or pharmacological mimicry can facilitate drug diversion. Drug manufacturers should employ unique visual standards that include…
Bayesian Individual Limits for IGF‐1 Monitoring in Equine Plasma: Implementation in the Equine Biological Passport
The Equine Biological Passport (EBP) summarizes the monitoring of biomarkers for selected racing horses in the context of anti-doping control.…
Multianalyte Approach—Including Automated Preparation of Calibrators—for Validated Quantification of 82 Drugs in Whole Blood by Liquid Chromatography–Tandem Mass Spectrometry
In forensic bioanalysis, often multianalyte approaches are used given their increased effectiveness but can be difficult to develop and maintain…
Evaluating the Effects of Solid‐Phase Cartridge Chemistry on Extraction of Bisphosphonates and ITPP From Equine Plasma
Bisphosphonate drugs and myo-inositol trispyrophosphate are of concern to the racing industry and have been listed as prohibited substances in…
Improving the Determination of Carbon Isotope Ratios of Endogenous Steroids Found in Human Serum
A method employing high-performance liquid chromatographic sample cleanup to determine the carbon isotope ratios of steroids found in human serum…
Carbon Monoxide Rebreathing as a Doping Method—A Toxic Debate
Drug Testing and Analysis, EarlyView.
Rapid Analytical Method for Quantification of Gamma‐Hydroxybutyrate (GHB) in Hair by UPLC‐MS/MS
A rapid and simple UPLC-MS/MS method for quantification of GHB in 10 mg of hair was developed. The method was satisfactorily…
Evaluation of Minimum Reporting Limits to Determine In‐Competition Use of Stimulants
Subjects were administered commonly prescribed doses of prescription stimulants once a day for 5 days. Urinary concentrations exceeded the MRL for…
Pharmacokinetics of Ethyl Glucuronide and Ethyl Sulfate and Pharmacodynamic Effects Following Intravenous and Oral Administration of Ethanol to Exercised Horses
This study describes the pharmacokinetics of ethanol metabolites following intravenous and oral administration to horses. Based on rapid metabolism, ethyl…