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Drug Test
  • September 22, 2024

High‐Throughput Equine Doping Controls on a Trapped Ion Mobility Quadrupole‐Time‐of‐Flight Mass Spectrometer: Technical Considerations of dia/slice/prmPASEF Applied to the Long‐Term Detection of Monoclonal Antibodies

Evaluation of three data acquisition strategies named diaPASEF, slicePASEF, and prmPASEF on a trapped ion mobility spectrometry quadrupole-time-of-flight (TIMS-Q-TOF) mass…
Drug Test
  • September 22, 2024

Pharmacokinetics of Two Formulations of Altrenogest Administered to Mares

Pharmacokinetics of altrenogest in mares to determine expected concentrations of plasma altrenogest associated with oral and intramuscular administration. Quantification of…
Drug Test
  • September 22, 2024

Suitability of Hair Testing in Medical Dispensing Errors: A Fatal Case of Gliclazide Poisoning

ABSTRACT A patient was prescribed a new treatment, 40 mg furosemide. Her pharmacist mistakenly dispensed 40 mg gliclazide instead. After 3 weeks…
Drug Test
  • September 20, 2024

Emerging Human Medications in Racing Animals: Analytical and Regulatory Challenges

A simple extraction followed by an LC-MS/MS method is presented to effectively screen for pregabalin and metformin, in addition to…
Drug Test
  • September 19, 2024

Doping Control Analysis of Perfluorocarbons in Equine Plasma by Headspace Gas Chromatography‐Tandem Mass Spectrometry

In order to control the potential misuse of perfluorocarbons as an oxygen carrier in equine sports, a simple and sensitive…
958:-sepsis-and-afib-heart-rate-differences-with-phenylephrine-vs-norepinephrine Healthcare
  • September 19, 2024

958: Sepsis and AFib heart rate differences with phenylephrine vs norepinephrine

Show notes at pharmacyjoe.com/episode958. In this episode, I’ll discuss differences in heart rate in patients with sepsis and AFib between…
Drug Test
  • September 17, 2024

Interest of Hair Tests to Discriminate a Tail End of a Voluntary Doping Regimen From the Use of a Contaminated Medicine in Case of Challenging an Antidoping Rule Violation. VI. Case Example With Trimetazidine

Drug Test
  • September 17, 2024

When Oxybutynin Becomes a Decoy for Oxycodone: A Case Report of Diversion Through Substitution

Drug substitution through visual or pharmacological mimicry can facilitate drug diversion. Drug manufacturers should employ unique visual standards that include…
Drug Test
  • September 16, 2024

Bayesian Individual Limits for IGF‐1 Monitoring in Equine Plasma: Implementation in the Equine Biological Passport

The Equine Biological Passport (EBP) summarizes the monitoring of biomarkers for selected racing horses in the context of anti-doping control.…
Drug Test
  • September 16, 2024

Multianalyte Approach—Including Automated Preparation of Calibrators—for Validated Quantification of 82 Drugs in Whole Blood by Liquid Chromatography–Tandem Mass Spectrometry

In forensic bioanalysis, often multianalyte approaches are used given their increased effectiveness but can be difficult to develop and maintain…