Pharmacokinetics of Two Formulations of Altrenogest Administered to Mares
Pharmacokinetics of altrenogest in mares to determine expected concentrations of plasma altrenogest associated with oral and intramuscular administration. Quantification of…
Suitability of Hair Testing in Medical Dispensing Errors: A Fatal Case of Gliclazide Poisoning
ABSTRACT A patient was prescribed a new treatment, 40 mg furosemide. Her pharmacist mistakenly dispensed 40 mg gliclazide instead. After 3 weeks…
Emerging Human Medications in Racing Animals: Analytical and Regulatory Challenges
A simple extraction followed by an LC-MS/MS method is presented to effectively screen for pregabalin and metformin, in addition to…
Doping Control Analysis of Perfluorocarbons in Equine Plasma by Headspace Gas Chromatography‐Tandem Mass Spectrometry
In order to control the potential misuse of perfluorocarbons as an oxygen carrier in equine sports, a simple and sensitive…
958: Sepsis and AFib heart rate differences with phenylephrine vs norepinephrine
Show notes at pharmacyjoe.com/episode958. In this episode, I’ll discuss differences in heart rate in patients with sepsis and AFib between…
When Oxybutynin Becomes a Decoy for Oxycodone: A Case Report of Diversion Through Substitution
Drug substitution through visual or pharmacological mimicry can facilitate drug diversion. Drug manufacturers should employ unique visual standards that include…
Bayesian Individual Limits for IGF‐1 Monitoring in Equine Plasma: Implementation in the Equine Biological Passport
The Equine Biological Passport (EBP) summarizes the monitoring of biomarkers for selected racing horses in the context of anti-doping control.…
Multianalyte Approach—Including Automated Preparation of Calibrators—for Validated Quantification of 82 Drugs in Whole Blood by Liquid Chromatography–Tandem Mass Spectrometry
In forensic bioanalysis, often multianalyte approaches are used given their increased effectiveness but can be difficult to develop and maintain…
Evaluating the Effects of Solid‐Phase Cartridge Chemistry on Extraction of Bisphosphonates and ITPP From Equine Plasma
Bisphosphonate drugs and myo-inositol trispyrophosphate are of concern to the racing industry and have been listed as prohibited substances in…